Oxidative stress is an aggravating factor in Lafora rare disease
Neurodegenerative Lafora disease usually becomes apparent through seizures during adolescence and puberty and occurs as a consequence of defects in glycogen metabolism and in the cellular mechanisms that are responsible for its disposal. Researchers at the University of Valencia have led a study in which they propose that Lafora could be aggravated by oxidative stress. These ideas have been put forward in a review article recently published in the journal Free Radical Biology and Medicine.
Neurodegenerative Lafora disease usually becomes apparent through seizures during adolescence and puberty and occurs as a consequence of defects in glycogen metabolism and in the cellular mechanisms that are responsible for its disposal. Researchers at the University of Valencia have led a study in which they propose that Lafora could be aggravated by oxidative stress. These ideas have been put forward in a review article recently published in the journal Free Radical Biology and Medicine.
SOURCE: Medical Xpress – Medical research News – Read entire story here.
