Researchers engineer E. coli to produce new forms of popular antibiotic

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1. Stem cell switch on the move The roots of a plant are constantly growing, so that they can provide the plant with water and minerals while also giving it a firm anchor in the ground. Responsible for these functions are pluripotent stem cells. In order to avoid differentiation and to remain pluripotent, these stem cells are dependent on signals from their neighboring cells. These signals are generated by only a small group of slowly dividing cells in the so-called quiescent centre inside the root. Biologists can now demonstrate how signals in plant roots determine the activity of stem cells....
2. ONT-380 has stage IV HER2+ breast cancer patient ‘worrying about normal stuff again’ Promising clinical trial results show activity of the investigational anti-cancer agent ONT-380 against HER2+ breast cancer, in one case specifically against brain metastases and in another case in overall survival of heavily pretreated HER2+ breast cancer patients....
3. Probiotic blocks staph bacteria from colonizing people At a Glance A probiotic reduced the amount of Staphylococcus aureus, or “staph,” bacteria in the......
4. Combining targeted drug with chemotherapy offers longer life to b-cell cancer patients Because of the significant benefit found in combining the targeted drug ibrutinib with standard chemotherapy for relapsed chronic lymphocytic leukemia or small lymphocytic lymphoma, an interim analysis has closed the international HELIOS phase III clinical trial....
5. Race influences warfarin dose A new report demonstrates that clinical and genetic factors affecting dose requirements for warfarin vary by race. The study proposes race-specific equations to help clinicians better calculate warfarin dosage....