New studies contradict earlier findings on Rett syndrome
Bone marrow transplant does not rescue mouse models of Rett syndrome, a severe neurological disease that affects very young girls, a new study shows. The findings contradict seemingly promising results published in 2012, which initiated a clinical trial for human patients. Rett syndrome is caused by mutations in the X-linked MECP2 gene and affects about 1 in every 10,000 girls (it is most often fatal in boys at or near birth). Rett syndrome causes many disabilities, both intellectual and physical.
Bone marrow transplant does not rescue mouse models of Rett syndrome, a severe neurological disease that affects very young girls, a new study shows. The findings contradict seemingly promising results published in 2012, which initiated a clinical trial for human patients. Rett syndrome is caused by mutations in the X-linked MECP2 gene and affects about 1 in every 10,000 girls (it is most often fatal in boys at or near birth). Rett syndrome causes many disabilities, both intellectual and physical.
SOURCE: Children’s Health News — ScienceDaily – Read entire story here.
